Strengths, shapes, when to use and more

If you suffer from migraine, your doctor may suggest Zomig as a treatment option.

Zomig is a prescription medication used to treat migraine headaches with or without aura. It is not used to prevent migraine episodes.

The active ingredient in Zomig is zolmitriptan. An active ingredient is what makes a drug work. Zomig belongs to the group of medicines called triptans, also known as serotonin receptor agonists.

This medication comes in three forms:

  • a pill you swallow
  • a tablet that dissolves in the mouth (called Zomig-ZMT orally disintegrating tablets)
  • a spray that you use in your nose

Adults can use all forms of Zomig. Only the nasal spray is suitable for some children.

This article describes Zomig dosages, along with its strengths and how to take the drug. To learn more about Zomig, check out this in-depth article.

To note: This table highlights the basics of the Zomig dosage. Be sure to read on for more details. And please keep in mind that this article covers standard Zomig dosages, which are provided by the drug manufacturer. But always follow the dosage instructions prescribed by your doctor.

This section covers common Zomig dosage and administration information. Before starting this medication, your doctor will discuss dosage instructions specific to your needs.

What are the forms of Zomig?

Zomig comes in three dosage forms:

  • Zomig tablets, which you swallow
  • Zomig-ZMT orally disintegrating tablets, which you dissolve on your tongue
  • Zomig nasal spray, which you spray into your nose

What are the strengths of Zomig?

Zomig tablets, Zomig-ZMT orally disintegrating tablets and Zomig nasal spray are available in two strengths:

What are the usual dosages of Zomig?

Usually your doctor will prescribe a low dose of Zomig. Then they will adjust your dosage over time to reach the right amount for you. They will ultimately prescribe the smallest dose that provides the desired effect.

The information below describes commonly used or recommended dosages. But be sure to take the dose your doctor has prescribed for you. They will determine the best dosage to meet your needs.

Here are the recommended starting dosages for Zomig:

  • Zomig tablet dosage: 1.25 mg or 2.5 mg as needed
  • Zomig-ZMT Orally Disintegrating Tablet Dosage: 2.5mg as needed
  • Dosage of Zomig nasal spray: 2.5mg as needed

You will take Zomig as a single dose when you experience a migraine episode. If after 2 hours your migraine is not relieved or if it comes back, you can take a second dose.

The maximum dose for all forms of Zomig is 5 mg per single dose and 10 mg total in 24 hours.

It is not known if it is safe to take either type of Zomig tablet for more than three migraine episodes per month on average. It is also not known if it is safe to use Zomig nasal spray for more than four migraine episodes per month.

What is the dosage of Zomig for children?

Zomig nasal spray can be used to treat migraine episodes in children aged 12 and over.

The recommended starting dose for children is 2.5 mg taken as needed. If your child is prescribed Zomig, they will take it as a single dose when they feel a migraine episode occurring. If after 2 hours their migraine is not relieved or if it comes back, they can take a second dose.

The maximum dose of Zomig nasal spray in children is 5 mg per single dose and 10 mg in total in 24 hours.

It is not known if it is safe to use Zomig nasal spray for more than an average of four migraine episodes per month.

Is Zomig used long term?

If you and your doctor determine that Zomig is safe and effective for you, they will likely prescribe it for the long term. But you will only take it if you have a migraine episode. They will tell you how many days per month you can take Zomig.

Dosage adjustments

Depending on how well your liver is working, you may need a reduced dose of Zomig. If you have certain types of liver problems, your doctor may not prescribe Zomig-ZMT orally disintegrating tablets or Zomig nasal spray.

The dosage of Zomig prescribed to you may depend on several factors. These include:

  • the severity of your migraine episode
  • your age
  • the form of Zomig you are using
  • other medicines you are taking
  • other conditions you may have (see ‘Dosage adjustments’ under ‘How much does Zomig do?’)

You will take your dose of Zomig at the start of a migraine episode. You can take a second dose 2 hours after your first dose if:

  • your migraine has not gone away, or
  • your migraine comes back after it has gone away

Note that you will only take Zomig when you have a migraine episode. You will not take this medicine every day.

Below are instructions on how to take each form of Zomig. For more information on taking this medication, consult your doctor or pharmacist.

For more information on expiration, storage and disposal of Zomig, see this article.

How to take Zomig tablets

To take Zomig tablets, you can swallow them whole with water.

If your dose of Zomig is 1.25mg, take half of a 2.5mg tablet. Each of these tablets has a marked line down the middle that you can use to cut or break the tablet in half.

If you have trouble swallowing tablets, see this article for advice on how to take this form of medication.

How to take Zomig-ZMT orally disintegrating tablets

To take Zomig-ZMT orally disintegrating tablets, follow these instructions:

  1. Keep the tablet in the blister pack until you are ready for your dose.
  2. Remove one tablet from the blister and place the whole tablet on your tongue. Do not split Zomig-ZMT tablets.
  3. Let the tablet dissolve in your mouth, then swallow it.
  4. Dispose of packaging safely.

How to use Zomig nasal spray

The following instructions explain how to use the Zomig nasal spray. There is only one dose in each bottle of Zomig nasal spray. Avoid pressing the plunger until you are ready for your dose.

  1. Gently blow your nose before using the nasal spray.
  2. Remove the nasal spray bottle from its packaging and remove the protective cap.
  3. Keeping your head straight, close one nostril with your index finger and exhale through your mouth.
  4. Hold the container with your other hand so that the bottom, which acts as a plunger, rests on your thumb. The nozzle should be between your index and middle fingers.
  5. Insert the tip of the nozzle into your open nostril as far as it will go.
  6. Tilt your head back slightly.
  7. Inhale through your nose while pressing firmly on the plunger with your thumb.
  8. Keep your head tilted back and remove the nozzle from your nose.
  9. Breathe gently through your mouth for a few seconds. You may feel liquid in your nose or throat. Its good.
  10. Safely dispose of the nasal spray.

Accessible medication containers and labels

If you have trouble reading the prescription label on your medications, talk to your doctor or pharmacist. Some pharmacies may provide medication labels that:

  • have large print or use Braille
  • feature a code you can scan with a smartphone to change text to audio

Your doctor or pharmacist may be able to recommend pharmacies that offer these accessibility features if your current pharmacy does not.

If you have difficulty opening medication blister packs, tell your pharmacist. They may have a few tips that can help simplify opening this package.

Do not use more Zomig than your doctor has prescribed. Using more than that can cause serious side effects.

It is not known if it is safe to take Zomig tablets for more than three migraine episodes in a 30 day period. It is also not known if it is safe to use Zomig nasal spray for more than four migraine episodes in 30 days.

Overdose symptoms

Symptoms caused by an overdose of Zomig may include drowsiness.

What to do if you take too much Zomig

Call your doctor right away if you think you have taken too much Zomig. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use their online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.

It is not known whether Zomig causes drug addiction. This is when your body develops a physical need for the drug. But using too much Zomig in a short period of time can cause medication overuse headaches.

You may be suffering from medication overuse headaches if:

  • you experience daily headaches similar to those you have during a migraine episode
  • you have more migraine episodes than usual

If you develop medication overuse headaches, your doctor will likely tell you to stop using Zomig. You may have withdrawal symptoms, such as a temporary worsening of migraines. Your doctor may prescribe a different medicine to treat these symptoms.

If you take more Zomig than recommended, tell your doctor. They can adjust your dosage or discuss if Zomig is right for you.

The sections above describe typical dosages provided by the drug manufacturer. If your doctor recommends Zomig, he will prescribe the dosage that is right for you.

Remember that you should not change your dose of Zomig without your doctor’s advice. Take Zomig exactly as prescribed. Talk with your doctor if you have any questions or concerns about your current dosage.

Here are some sample questions you may want to ask your doctor:

  • Should I take a higher dose of Zomig if the medicine is not working well enough for me?
  • Would my dosage be different if I switched from Zomig tablets to Zomig nasal spray?
  • What should I do if I still have migraine symptoms after taking a second dose of Zomig?

For more information on migraine treatments and tips on managing your condition, sign up for Healthline’s online newsletter. And if you want to connect with other migraine sufferers, consider joining the Bezzy Migraine Community.

Disclaimer: Healthline has made every effort to ensure that all information is factually correct, complete and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or for all specific uses.

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