Shapes, strength, how to use, and more

Humulin N (Insulin Isophane Human) is a Food and Drug Administration (FDA) approved brand name drug to treat type 1 diabetes and type 2 diabetes. It can be used in adults and children.

Humulin N comes as a liquid suspension that you inject subcutaneously using a KwikPen or vial and syringe. Humulin N is available over-the-counter or your doctor can prescribe it.

This medicine belongs to a group of biological medicines called intermediate-acting insulins. It is only available in branded form. There are currently no biosimilar forms of Humulin N.

Dosage table

The following Humulin N dosage chart summarizes the forms, strength, and recommended dosage of the drug. However, your doctor will determine the specific dosage that is best for you.

For more information on Humulin N dosage, including how to inject the drug, keep reading. For a complete overview of Humulin N, check out this article.

Your Humulin N dosage will depend on many factors, including the severity of your diabetes and how you respond to the medication. Talk to your doctor about the best Humulin N dosage for you.

Forms of humulin N

Humulin N comes as a liquid suspension injected subcutaneously. It comes in two forms: a bottle and an injection pen called Humulin N KwikPen.

Humulin N vials are available in 3 milliliter (mL) and 10 mL sizes. The KwikPen only comes as a 3ml pen.

Strength of humulin N

Humulin N is available in one strength, 100 units of insulin per milliliter of fluid. This is also written as 100 units/mL or U-100.

Typical dosages for diabetes

The manufacturer of Humulin N does not make specific dosage recommendations. Your doctor will determine the best dosage to meet your needs. They will base your dosage on the severity of your diabetes, your blood sugar levels, and other factors.

Typically, you will have a low starting dose. Depending on your blood sugar levels during the first few weeks of treatment with Humulin N, your doctor will likely adjust your dosage until your blood sugar levels are within your target range. And they may continue to adjust your dosage throughout your Humulin N treatment.

Taking other diabetes medications, including other forms of insulin, and changes to your diet, exercise level, or general health may also affect your Humulin N dosage. (See “Factors That May Affect Your Dosage” below for details.) Your doctor will ultimately prescribe the smallest dose that produces the desired effect.

The following sections describe commonly used or recommended Humulin N dosage ranges. However, be sure to take the dose prescribed by your doctor. They may have you injected with Humulin N once a day or take your daily dose in two injections.

Dosage for type 1 diabetes

The recommended insulin dose for type 1 diabetes is 0.4 to 1 unit of insulin per kilogram (kg)* of body weight per day. Basal insulin such as Humulin N should be about half of your daily insulin. The table below gives commonly recommended Humulin N dosage ranges.

* One kg is approximately 2.2 pounds (lb).

Dosage for type 2 diabetes

For basal insulins like Humulin N, 0.1 to 0.2 units of insulin per kg body weight per day is the recommended dosage range for type 2 diabetes. The table below gives the dosage ranges of Humulin N which are commonly recommended.

Dosages for children

The manufacturer of Humulin N does not make specific dosage recommendations for children with diabetes. Your child’s doctor will determine their dose based on the severity of their diabetes, blood sugar levels, weight and age, and other factors. (See “Factors That May Affect Your Dosage” below for details.)

The recommended insulin doses for children are as follows:

  • For type 1 diabetes: 0.7 to 1 unit of insulin per kilogram (kg)* of body weight per day. Basal insulin like Humulin N should make up about 30-45% of your child’s daily insulin.
  • For type 2 diabetes: 0.25 to 0.5 units of insulin per kg of body weight per day.

The table below gives the Humulin N dosage ranges that are commonly recommended for children.

If you want more information about the best Humulin N dosage for your child, talk to their doctor.

* One kg is approximately 2.2 pounds (lb).

Long term treatment

Humulin N is intended for use as a long-term treatment. If you and your doctor determine that Humulin N is safe and effective for you, you are likely to use it long term.

The dose of Humulin N prescribed by your doctor will depend on several factors. These include:

  • the type and severity of your diabetes
  • your target blood sugar
  • other medicines you are taking
  • your diet and exercise habits
  • your weight
  • your age

Other medical conditions you have may also affect your dose of Humulin N.

Dosage adjustments

Your doctor may recommend adjustments to your dose of Humulin N in certain situations. Be sure to tell your doctor if you develop any changes in your general health, especially any of the following:

  • kidney problems
  • liver problems
  • changes in other medicines you take, including other forms of insulin
  • changes in your diet or exercise habits
  • changes in your weight

You should adjust your dose of Humulin N only as recommended by your doctor. Be sure to monitor your blood sugar regularly and let your doctor know of any significant changes.

Humulin N is given by injection under the skin once or twice a day. Before you start treatment with Humulin N, your doctor or pharmacist will show you how to inject your dose.

The medicine should be injected at about the same time(s) of the day. This helps maintain a constant level of the drug in your body, which helps keep your blood sugar levels constant.

Humulin N liquid suspension comes in two forms:

  • A KwikPen. You will attach a pen needle to the KwikPen and use a dial on the pen to select the prescribed dose.
  • Vials. You will attach a needle to an insulin syringe and use it to withdraw the prescribed dose.

You can inject Humulin N into the abdomen, thigh, upper arm, or buttocks. Be sure to change the injection site with each dose to reduce the risk of side effects. For example, if you inject a dose into your abdomen, use another part of your abdomen for the next injection or another area of ​​the body. And be sure to use a new needle for each dose.

For step-by-step guidance, see the manufacturer’s instructions on how to use Humulin N or KwikPens vials.

Be sure to check your blood sugar as recommended by your doctor. They might ask you to check your levels more frequently when you start treatment or after adjusting your dosage.

Accessible medication labels and containers

If you have trouble reading your prescription label, talk to your doctor or pharmacist. Some pharmacies offer labels in large print, Braille, or with a code you scan with a smartphone to convert text to speech. If your local pharmacy does not offer these options, your doctor or pharmacist may be able to recommend a pharmacy that does.

If you miss a dose of Humulin N, talk to your doctor or pharmacist. In some cases, they may recommend taking your dose as soon as you remember. However, if it is almost time for your next dose of Humulin N, they may recommend that you skip the missed dose and inject your next dose at the usual time.

To make sure you don’t miss a dose, try using a medication reminder. This may include setting an alarm or using a timer. You can also download a reminder app on your phone.

If you use more Humulin N than your doctor has prescribed, you may develop serious side effects. It is important that you do not inject more medicine than your doctor has advised.

Symptoms of an overdose

Symptoms of Humulin N overdose may include low blood sugar or low potassium, which may lead to:

  • dizziness
  • sweat
  • fatigue
  • muscle twitching or weakness

If you use more than the recommended amount of Humulin N

Call your doctor right away if you think you injected too much Humulin N. Another option is to call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

The dosages in this article are typical dosages provided by the drug manufacturer. If your doctor recommends Humulin N, he will prescribe the dosage that is right for you. Always follow the dosage prescribed by your doctor.

As with any medication, never change your dose of Humulin N without consulting your doctor. If you have any questions about the dose of Humulin N that is right for you, talk to your doctor.

In addition to knowing more about dosing, you may want other information about Humulin N. These additional resources might be helpful:

Disclaimer: Medical News Today has made every effort to ensure that all information is factually correct, complete and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or for all specific uses.

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