Integrated health system pharmacy models associated with medication adherence, fewer side effects

Patient-reported outcomes were positive for those refilling medications at a specialty pharmacy in the integrated health system.

According to a poster displayed at the American Society of Health-System Pharmacists (ASHP) Summer Meetings and Expos, held June 11-15, 2022, in Phoenix, Arizona.

To determine whether patient-reported outcomes are associated with patient-perceived drug efficacy in a healthcare system specialty pharmacy setting, researchers conducted a single-center retrospective analysis of patients who were prescribed specialty medications. in rheumatology, multiple sclerosis, neurology, dermatology, or asthma and allergy clinics. Outcomes were assessed after the patient completed 2 medication refill questionnaires over a 3-month period (January to March 2020).

The primary study outcomes were the frequency of patient-reported outcomes related to perceived medication effectiveness, missed doses, and medication side effects. Researchers used electronic health records to collect demographic and medication prescription data, while patient-reported outcomes and pharmacist intervention data were collected from a patient management database. patients in specialized pharmacies.

The cohort included 1398 patients in 6 specialty pharmacy clinics (66% female; 86.5% Caucasian; mean age: 56 years). Just over 50% of patients came from the rheumatology clinic, while asthma and allergy sufferers made up only 3.3% of the patient population.

A total of 4,125 medication refill questionnaires were completed, with a total of 172 missed doses reported, most often due to instructions to save medication for illness or medical procedures.

Patients reported side effects only 41 times (1%); most rated the effectiveness as good or excellent (72% and 25%, respectively). Among those who did not report side effects, the odds of reporting greater effectiveness were 7.49 times higher than those who did (95% CI, 3.31-16.95). Similarly, patients who did not report a missed dose were 2.13 times more likely to report higher efficacy (95% CI, 1.42-3.19).

“Patients refilling specialty medications in an integrated health systems pharmacy model reported low rates of missed doses and side effects,” the researchers concluded. “Furthermore, patients who did not report missed doses or side effects were significantly more likely to have higher perceived treatment efficacy.”


Brian ED. Evaluate patient-reported outcomes in a specialty pharmacy in the integrated health system. Presented at: American Society of Health-System Pharmacists Summer Meetings & Exhibition; June 11-15, 2022; Phoenix, AZ. Poster 40-M.

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