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Treximet (sumatriptan/naproxen) is a brand name prescription drug. The Food and Drug Administration (FDA) has approved it to treat migraine with or without aura. The drug is prescribed for adults as well as for children aged 12 and over.

Treximet comes in the form of an oral tablet. It contains two active drugs: sumatriptan and naproxen. Sumatriptan belongs to a class of medications called triptans. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). Treximet is available as a generic called sumatriptan/naproxen.

Dosage Summary

The following table summarizes the dosage of Treximet. Milligrams are abbreviated as mg. Your doctor will determine the dosage that is best for you.

For more information on Treximet doses for migraine, including drug strength and how to take it, keep reading. For a complete overview of Treximet, check out this article.

This article outlines typical doses of Treximet provided by the drug’s manufacturer. When taking Treximet, always follow the dosage prescribed by your doctor.

Here is some information about Treximet dosages.

Treximet form

Treximet comes in the form of an oral tablet.

Strength of Treximet

Treximet has a strong point. Each tablet contains 85 mg of sumatriptan and 500 mg of naproxen.

Typical dosages

The following information describes commonly used or recommended dosages. However, be sure to take the dose prescribed by your doctor. Your doctor will determine the best dosage to meet your needs.

The typical dose of Treximet for adults is one 85 milligram (mg)/500 mg tablet. It is taken at the start of a migraine episode. If this dose does not provide enough relief or if the migraine episode comes back, you can take a second tablet 2 hours after the first tablet. However, if the first dose does not relieve your migraine episode, you should not take a second dose. Instead, talk to your doctor.

The maximum dose in a 24 hour period is two tablets, taken at least 2 hours apart. Be sure to follow your doctor’s dosage instructions for Treximet.

Dosage for children

The maximum recommended dose of Treximet for children aged 12 years and over is one 85mg/500mg tablet. The drug is taken at the start of a migraine episode. It is not known if treating more than two migraine episodes with Treximet every 30 days works or is safe for children.

The recommended dose of Treximet for children aged 12 years and over was previously one 10mg/60mg tablet. This power is no longer available.

If you have any questions about the dosage of Treximet for your child, talk to their doctor.

Long term treatment

Treximet is meant to be a long-term treatment. If you and your doctor determine that Treximet is safe and effective for you, you are likely to take it long term.

Keep in mind that the safety of taking Treximet for a migraine more than five times in a 30 day period is not known. Talk to your doctor if you take Treximet more than five times in a 30 day period. You may benefit from a different medication for migraines.

Be sure to follow your doctor’s dosage instructions for Treximet.

You will swallow Treximet tablets whole with a glass of water or other liquid. If you have trouble swallowing tablets, see this article for advice on how to take this form of medication. You can also discuss this with your doctor or pharmacist.

Keep in mind that you can take Treximet with or without food.

Your doctor may ask you to take your first dose in their office if both of these situations apply:

Taking your first dose in your doctor’s office allows him to monitor you for any Treximet side effects. To learn more about the side effects of the drug, check out this article.

If your first dose does not provide enough relief or if the migraine episode comes back, you can take a second tablet 2 hours after the first tablet. However, if the first dose does not relieve your migraine episode, you should not take a second dose. Instead, talk to your doctor. It is important that you do not take more than two doses of Treximet in a 24 hour period.

Follow-up migraine

Try to find out when you are having a migraine episode and when you are taking Treximet. This can help you know if the medicine is working. You can keep a written diary or enter the dates on a calendar on your phone. A migraine app can also be helpful.

Accessible medication labels and containers

If you have trouble reading your prescription label, talk to your doctor or pharmacist. Some pharmacies offer labels in large print, Braille, or with a code you scan with a smartphone to convert text to speech. If your local pharmacy does not offer these options, your doctor or pharmacist may be able to recommend a pharmacy that does.

If you have difficulty opening medicine bottles, ask your pharmacist to put Treximet in an easy-open container. They can also recommend tools that can make opening bottles easier.

The dosage of Treximet prescribed by your doctor will depend on several factors. These include:

  • the type and severity of your migraine episodes
  • how well your liver is working
  • other medical conditions you may have
  • your age

If you take more Treximet than your doctor has prescribed, you may develop serious side effects.

It is important that you do not take more Treximet than your doctor has advised.

Symptoms of an overdose

One of the active drugs of Treximet is naproxen. Symptoms of Treximet overdose due to naproxen may include:

  • Extreme tiredness
  • lack of energy
  • nausea
  • vomiting
  • abdominal pain
  • bleeding in the stomach or intestines

Symptoms of Treximet overdose that are rare may include:

If you take more than the recommended amount of Treximet

Call your doctor right away if you think you have taken too much Treximet. Another option is to call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.

The dosages in this article are typical dosages provided by the drug manufacturer. If your doctor recommends Treximet, he will prescribe the dosage that is right for you. Always follow the dosage prescribed by your doctor.

As with any medication, never change your dose of Treximet without your doctor’s advice. If you have any questions about which dosage of Treximet is right for you, talk to your doctor.

Besides learning the dosage, you may want other information about Treximet. These additional articles might be helpful:

Warning: Medical News Today has made every effort to ensure that all information is factually correct, complete and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or for all specific uses.

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