Dosage, cost, side effects, etc.

Here are the answers to some frequently asked questions about Tezspire.

How do Tezspire and Dupixent compare?

Tezspire and Dupixent are complementary (long-term) maintenance treatments for severe asthma. Doctors prescribe them to people whose asthma is not adequately controlled by other treatments. Both drugs are given by subcutaneous injection. But there are key differences between Tezspire and Dupixent.

Tezspire is prescribed for people aged 12 and over with all types of severe asthma. You will usually receive it every 4 weeks. Doctors prescribe Dupixent to people aged 6 and over with moderate to severe asthma:

Dupixent is usually taken every 2 weeks. This medication also treats moderate to severe eczema and chronic rhinosinusitis with nasal polyps.

Tezspire contains the active drug tezepelumab-ekko, while Dupixent contains the active drug dupilumab. Both are biological drugs called monoclonal antibodies. Biologics are drugs made from living cells. And monoclonal antibodies block the activity of certain proteins in the body. But Tezspire and Dupixent block different proteins involved in inflammation.

If you want to know more about the comparison between Tezspire and Dupixent, talk to your doctor.

Should I use Tezspire if I have a sudden asthma attack?

Tezspire should not be used to treat a sudden onset of asthma. It is not a rescue medicine (a medicine used to relieve shortness of breath or asthma attacks). Tezspire will not relieve sudden breathing problems.

Tezspire is a long-term maintenance treatment that helps prevent asthma flare-ups. If you have a scheduled dose of Tezspire but have a sudden onset of asthma, you can still receive your dose of Tezspire. However, this will not relieve your respiratory problems.

If you have a sudden asthma attack, you should use your reliever medication as prescribed by your doctor. Consult your doctor if your asthma symptoms do not improve or worsen after starting Tezspire.

Will I still need to take my other asthma medications daily with Tezspire?

Yes, you will probably need to continue taking your daily asthma medications while taking Tezspire. For information on other medicines you may take with Tezspire, see ‘Using Tezspire with other medicines’ below.

Tezspire is a maintenance (long-term) treatment that helps prevent asthma flare-ups. It is used as a complementary treatment, which means that you will receive it together with your current asthma medication.

In some cases, your doctor may recommend that you stop certain other asthma medicines if your asthma improves with Tezspire. But you should not make any changes to your asthma medication, especially any corticosteroids you take, without first discussing this with your doctor. Stopping your other asthma treatments or reducing your doses could make your asthma worse. This could lead to a sudden asthma flare-up.

Talk to your doctor if you have any questions about taking other asthma medicines together with Tezspire.

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