Daily Medication Pearl: Risperidone (Risperdal Consta)

Risperidone (Risperdal Consta) is an atypical antipsychotic that can treat schizophrenia, bipolar disorder, and irritability caused by autism.

Pearl of the day medication: Risperidone (Risperdal Consta)

Indication: Risperidone (Risperdal Consta) is an atypical antipsychotic that can treat schizophrenia, bipolar disorder, and irritability caused by autism.

Insight:

  • Dosage: Administer intramuscularly 25 mg intramuscularly every 2 weeks.
  • Dosage forms: Kits of 12.5 mg, 25 mg, 37.5 mg and 50 mg vials.
  • Adverse events: The most common adverse reactions in clinical trials in patients with schizophrenia (≥5%) were headache, parkinsonism, dizziness, akathisia, fatigue, constipation, dyspepsia, sedation, weight, pain in the extremities and dry mouth. The most common adverse reactions in clinical trials in patients with bipolar disorder were weight gain (5% in the monotherapy trial) and tremor and parkinsonism (≥10% in the treatment trial). extra).
  • Action mechanism: The mechanism of action of risperidone, like other drugs used to treat schizophrenia, is unknown. However, the therapeutic activity of the drug in schizophrenia has been proposed to be mediated by a combination of dopamine type 2 and serotonin type 2 receptor antagonism.
  • Maker: Janssen

Reference:

Risperdal Consta label (fda.gov)

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